Kidney Function Tests in Children with Beta-Thalassemia Minor in Zahedan, Southeast of Iran

Authors

  • Simin Sadeghi-Bojd Department of Pediatrics, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Author
  • Mohammad Hashemi Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Author
  • Majid Naderi Department of Pediatrics, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Author
  • Shahriar Shikhani Department of Pediatrics, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Author

Abstract

There is little information regarding kidney function in patients with beta-thalassemia minor. In this study we investigated kidney function tests in 50 children with beta-thalassemia minor (22 boys and 28 girls). Twenty-four-hour urine samples were collected and analyzed for sodium, potassium, calcium, magnesium, creatinine, phosphate, uric acid, protein, and beta2-microglobulin. Blood samples were obtained for hematologic and biochemical analyses including complete blood count, serum ferritin, sodium, potassium, calcium, phosphate, magnesium, creatinine, and uric acid. This group of children with beta-thalassemia showed some evidence of tubulopathy such as proteinuria (32%), beta2-microglobulin excretion (36%), calciuria (4%), phosphaturia (4%), and uricosuria (20%). Our findings support the existence of renal tubular dysfunction in beta-thalassemia minor. However, further studies in large series are needed to shed light on the possible relation of these two distinct diseases.

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Published

2011-04-26

Issue

Section

BRIEF COMMUNICATION | Kidney diseases

How to Cite

Kidney Function Tests in Children with Beta-Thalassemia Minor in Zahedan, Southeast of Iran. (2011). Iranian Journal of Kidney Diseases, 5(3), 201-203. https://ijkd.org/index.php/ijkd/article/view/400