Association of Serum Uric Acid With Level of Blood Pressure in Type 2 Diabetic Patients

Authors

  • Mahmoud Rafieian-Kopaei Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran Author
  • Saeed Behradmanesh Department of Internal Medicine, Division of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran Author
  • Soleiman Kheiri Department of Internal Medicine, Division of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran Author
  • Hamid Nasri Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran Author

Abstract

This study was conducted to investigate the association between serum uric acid level and blood pressure in type 2 diabetes mellitus. Sixty patients with type 2 diabetes mellitus were enrolled to the study. None of the patients had a history of gout, were treated with allopurinol, or were treated with antihypertensive drugs previously. The mean duration of DM was 9.2 ± 4.9 years. The mean serum creatinine level was 0.98 ± 0.22 mg/dL, and the mean serum UA level was 4.4 ± 1.2 mg/dL. The mean protein level in 24-hour urine sample was 388 ± 22 mg/d. The mean systolic and diastolic blood pressure values were 133.0 ± 13.0 mm Hg and 84.0 ± 7.4 mm Hg, respectively. There was no significant difference in levels of serum uric acid, hemoglobin A1c, serum creatinine, proteinuria, or systolic and diastolic pressure between the men and the women. A significant positive correlation was seen between serum UA and systolic (r = 0.312, P = .02) and diastolic blood pressure (r = 0.297, P = .03). Results of this study suggest that serum uric acid had a strong association with levels of systolic and diastolic blood pressure in type 2 diabetic patients. More attention to the serum uric acid level and treatment of hyperuricemia could halt the progress of diabetic nephropathy.

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Published

2014-03-20

Issue

Section

BRIEF COMMUNICATION | Kidney diseases

How to Cite

Association of Serum Uric Acid With Level of Blood Pressure in Type 2 Diabetic Patients. (2014). Iranian Journal of Kidney Diseases, 8(2), 152-154. https://ijkd.org/index.php/ijkd/article/view/1346

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