Management of Idiopathic Retroperitoneal Fibrosis, a Retrospective Study at Prince Hussein Urology and Organ transplantation center (PHUO), Jordan

Authors

  • Firas Ahmed Al-Hammouri Urology Department, Prince Hussein Bin Abdullah For Urology and Organ Transplant Center- King Hussein Medical Center, Jordan Author
  • Firas Azar Khori Author
  • Adnan Abedalqader Abu Qamar Author
  • Abedelhakim Nimate Author
  • Awad Bakheet Kaabneh Author
  • Ashraf Almajali Author
  • Ali Zraigat Author
  • Abdullah Alomari Author

Abstract

Introduction. to study the presentation, clinical course, laboratoryresults, imaging findings, medical and urological treatments ofidiopathic retroperitoneal fibrosis at our institution.Methods. Between January 2006 and December 2017, medical recordsand operatives' notes of 116 patients with idiopathic retroperitonealfibrosis (IPRF) were reviewed retrospectively. Diagnosis was doneby clinical and radiological imaging that fulfilled a strict criterion.All patients were initiated on Prednisolone 60 mg for two months,and reduced until reaching 10 mg daily, with a total duration of24 months in the responding patients. Renal drainage was done incases of obstructed kidneys. To assess response, both laboratoryresults and imaging studies at initiation and after 4 months werereviewed and compared.Results. Of 116 patients diagnosed with IRPF, eighty five (73.3%)were male and thirty one (26.7%) female, with mean ┬▒ SD age atpresentation was (50.5 ┬▒ 10.6) years. 79% of the patients complaintof abdominal and low back pain, 27% uremic symptoms, 10.3% hada new onset of hypertension, 3.4% presented with anejaculation,and 13.8% were totally asymptomatic. Uretric obstruction hadbeen resolved in 132 ureters after a mean of 152 days of treatment.Almost 30 % reduction in the fibrotic mass size was achieved in82 % of patients.Conclusion. Glucocorticoids is the the mainstay of treatment. Therenal function tests, of the vast majority of patients, normalizedwith treatment. Relapse may occur, so a follow-up over a longperiod of time is required. A high index of suspicion is neededfor diagnosis in asymptomatic patients.

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Author Biographies

  • Firas Ahmed Al-Hammouri, Urology Department, Prince Hussein Bin Abdullah For Urology and Organ Transplant Center- King Hussein Medical Center, Jordan
    • Firas Al-Hammouri FEBU, FACS, JBU, JBS

    • Urology Consultant. Prince Hussein Bin Abdullah Urology Center

    • Laparoscopic Oncology and Endourology fellowship- Germany

    • European Board of Urology

    • Fellow of the American College of Surgeons

    • Jordanian Board of Urology

    • Jordanian Board of general Surgery

    • Faculty member of the Royal College of Surgeons- England

    • Member of the American College of Surgeons

    • Member of the European Association of Urology

    • Member of the Arab Association of Urology

    • Member of the Middle East Society For Organ Transplantation┬á

    • Member of the Jordanian Society for Fertility and Genetics

    • Member of the Jordanian Urology Group

    • Member of the Jordanian General Surgery Group.

    • Member of Jordan Medical Association.

  • Firas Azar Khori

    Urology Consultant

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Adnan Abedalqader Abu Qamar

    Urology Consultant

    Head Of Urology Department

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Abedelhakim Nimate

    Urology specialist

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Awad Bakheet Kaabneh

    Urology Consultant

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Ashraf Almajali

    Urology specialist

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Ali Zraigat

    Urology specialist

    Prince Hussein Bin abdullah for Urology and Organ Transplant Center

  • Abdullah Alomari

    Radiology Consultant

    Head Of Radiology Department

    King Hussein Medical Center

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Published

2019-08-17

Issue

Section

ORIGINAL | Kidney Diseases

How to Cite

Management of Idiopathic Retroperitoneal Fibrosis, a Retrospective Study at Prince Hussein Urology and Organ transplantation center (PHUO), Jordan. (2019). Iranian Journal of Kidney Diseases, 13(4), 251-256. https://ijkd.org/index.php/ijkd/article/view/4396