Genetics and Epigenetics of Chronic Allograft Dysfunction in Kidney Transplants
Abstract
Chronic allograft dysfunction is the most common cause of allograft lost. Chronic allograft dysfunction happens as a result of complex interactions at the molecular and cellular levels. Genetic and environmental factors both influence the evolution and progression of the chronic allograft dysfunction. Epigenetic modification could be considered as a therapeutically modifiable element to pause the fibrosis process through novel strategies. In this review, the PubMed database was searched for English-language articles on these new areas.
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Published
2016-01-29
Issue
Section
REVIEW | Transplantation
How to Cite
Genetics and Epigenetics of Chronic Allograft Dysfunction in Kidney Transplants. (2016). Iranian Journal of Kidney Diseases, 10(1), 1-9. https://ijkd.org/index.php/ijkd/article/view/2151