Effects of alcohol, esomeprazole and dried alum on the gastric glands of mice

Sonnenberg A, Lash RH, Genta RM. A national study of Helicobactor pylori infection in gastric biopsy specimens. Gastroenterology 2010; 139: 1894-1901 [PMID: 20727889 DOI:10.1053/j.gastro.2010.08.018]

Park YH, Kim N. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev 2015; 20: 25-40 [PMID: 25853101 DOI: 10.15430/JCP.2015.20.1.25]

Boss GR，Seegmiller JE． Age-related physiological changes and their clinical significance［J］． West J Med，1981，135 (6): 434-440．

Chooi EY，Chen HM，Miao Q，et al． Chronic atrophic gastritis is a progressive disease: analysis of medical reports from Shanghai (1985-2009) ［J］． Singapore Med J，2012，53 (5): 318-324．

Tadashi Hagiwara, Ken-Ichi Mukaisho, Takahisa Nakayama, Hiroyuki Sugihara, Takanori Hattori. Long-term proton pump inhibitor administration worsens atrophic corpus gastritis and promotes adenocarcinoma development in Mongolian gerbils infected with Helicobacter pylori. Gut 2011 May; 60(5):624-30. doi: 10.1136/gut.2010.207662. Epub 2010 Nov 20.

Corso G, Seruca R, Roviello F. Gastric cancer carcinogenesis and tumor progression. Ann Ital Chir 2012;83: 172-176 [PMID: 22595727]

Plaks V，Brenot A，Lawson DA，et a1．Lgr5-expressing cells are sufficient and necessary for postnatal mamma-rygland organogenesis[J1．Cell Rep，2013，3(1)：70-78．

Mardaryev AN，Meier N，Poterlowicz K，et a1．Lhx2 differentially regulates Sox9．Tcf4 and Lgr5 in hair folliclestem cells to promote epidermal regeneration after injury[J]，Development，2011，138(22)：4843—4852．

Nakata S，Campos B，Bageritz J，et a1．LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells[J]．Brain Pathol，2013，23(1)：60-72．

De Visser KE，Ciampricotti M，Michalak EM，et a1．Developmental stage—specific contribution of LGR5+cells tobasal and luminal epithelial lineages in the postnatal mam-mary gland[J]．J Pathol，2012，228(3)：300-309．

Gong，Xing，Azhdarinia，A，Ghosh Sukhen C，et a1．Lgr5-Targetef Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence[J]．Mol Cancer Ther，2016，15(7)：1580-1590．

Barker N，Huch M，Kujala P，et a1．Lgr5(+ve)stem cells drive selfrenewal in the stomach and build long—lived gastric units in vitro[J]．Cell Stem Cell，2010，6(1)：25—36．

Hussent T, Dali S, Exinger J, et al. SOX2 is an oncogene activated by recurrent 3q2 6.3amplifications in human lung squamous cell carcinomas [J]. PLoS One, 2010, 5(1): e8960.

Mann CD, Neal CP, Garcea G, et al. Prognostic molecular markers in hepatocellular carcinoma: a systematic review [J]. Eur J Cancer，2007, 43(6): 979-992．

Pijnappel WW, Esch D, Baltissen MP, et al. A central role for TFIID the pluripotent transcription circuitry [J]. Nature, 2013, 495(7442):516-519.

Reya T, Morrison SJ, Clarke MF, et al. Stem cells cancer and cancer stem cells [J]. Nature, 2012, 414(6859): 105-111